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49ers LT Staley Injured Against Colts

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Nov 1, 2009 2:26 pm US/Pacific

49ers LT Staley Injured Against Colts

INDIANAPOLIS, Indiana (CBS 5 / AP) ―

Click to enlarge 1 of 1: 49ers left tackle Joe Staley was injured in Sunday's game against the Colts.
Jonathan Daniel/Getty Images

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San Francisco left tackle Joe Staley sprained his right knee on the first play Sunday against the Colts, and did not return.

Staley has started every game of his three-year career. Barry Sims stepped in for him.

The 49ers already have lost right tackle Tony Pashos for the season with a broken left shoulder blade. Pashos was hurt during last week's 24-21 loss at Houston.

San Francisco coach Mike Singletary has called the offensive line his biggest area of concern.